For treating chronic hepatitis C in adults, a number of medications are used. Among those various medications is daclatasvir, a Hepatitis C Virus NS5A Inhibitor. Available orally, daclatasvir demonstrates potential activity against HCV.
Medically, HCV is a tiny, enclosed, single-stranded RNA virus that belongs to the Flaviviridae family. Daclatasvir is an antiviral medicine that averts HCV from multiplying.
Daclatasvir Prices in Russia
There are two popular daclatasvir brands available in Russia, Dactovin and Daclahep. Price for one bottle of these medications can range anywhere from 2280 to 2420 Ruble.
NS5A plays a pivotal role in HCV RNA replication. Post intracellular uptake, daclatasvir binds to the domain I of the NS5A protein. Doing so results into inhibiting the activity of the NS5A protein that causes:
- Blockage of the viral HCV RNA production,
- Disruption of the viral RNA replication complex, and
- Inhibition of the viral replication
60 mg is taken orally once in a day.
Usually, daclatasvir is given with sofosbuvir to adults suffering from chronic Hepatitis C. Ribavirin may or may not be given with the two popular HCV medications.
For HCV patients with a hepatitis B history, daclatasvir might bring back the condition and even worsen it. In such a case, frequent blood tests might be required to keep a check on liver function.
Do not stop taking daclatasvir suddenly as this might make the HCV harder to treat with other antiviral medicine.
Before Taking Daclatasvir
Avoid taking Daclatasvir if you are allergic to it. Some medications while taken separately to daclatasvir might interact for the worse. Consult a doctor if taking daclatasvir clashes with other medications you are currently having.
How to Take Daclatasvir
Daclatasvir must be taken in combination with sofosbuvir and should not be taken alone. Typically, daclatasvir is taken with other types of antiviral medicines in one-dose-per-day regime for 12 weeks.
Daclatasvir can be taken with or without food. Usually, doctors perform blood tests for ensuring it is safe to prescribe the antiviral agent.
There a wide variety of side effects of daclatasvir. You need to consult your physician as soon as you start experiencing one or several of these:
- Clay-colored stools
- Cold hands and feet
- Dark urine
- Difficulty in breathing
- Loss of appetite
- Memory problems
- Swelling on the face, lips, throat or tongue
- Unusual fatigue
Where to buy?
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Related: know how to buy medicine online