Velpanat Tablets

Product Description

Velpanat Tablets: Uses, Side Effects, and Warnings

Velpanat Tablets are a fixed-dose combination of sofosbuvir and velpatasvir, two direct-acting antiviral (DAA) medications. Velpanat Tablets are used to treat chronic hepatitis C virus (HCV) infection in adults. HCV is a liver infection that can cause serious liver damage, including cirrhosis and hepatocellular carcinoma (HCC), if left untreated.

How Velpanat Tablets Work?

Sofosbuvir and velpatasvir work by blocking the HCV virus from replicating in the body. This helps to clear the virus from the body and prevent liver damage. Sofosbuvir and velpatasvir are highly effective antiviral medications, and most patients who take Velpanat Tablets achieve a sustained virologic response (SVR), which is the functional cure of HCV infection.

Dosage and Duration of Treatment

The recommended dosage of Velpanat Tablets is one tablet taken orally once daily with or without food. The duration of treatment depends on the patient's individual circumstances, including the genotype of the HCV virus and the presence of cirrhosis. Most patients are treated with Velpanat Tablets for 8 or 12 weeks.

Efficacy and Safety

Velpanat Tablets are a highly effective and safe treatment for chronic HCV infection. In clinical trials, Velpanat Tablets achieved SVR rates of over 95% in most patients. Velpanat Tablets are also very well-tolerated, with few side effects. The most common side effects of Velpanat Tablets are mild and go away on their own within a few days or weeks. These side effects may include:

• Fatigue
• Headache
• Nausea
• Diarrhea
• Insomnia

Less common side effects of Velpanat Tablets may include:

• Anemia
• Leukopenia
• Thrombocytopenia
• Pancreatitis
• Liver damage
• Kidney damage
• Lactic acidosis

Drug Interactions

Velpanat Tablets may interact with other medications, so it is important to tell your doctor about all of the medications you are taking before starting Velpanat Tablets. Some medications that may interact with Velpanat Tablets include:

• Amiodarone
• Atazanavir
• Carbamazepine
• Ethinyl estradiol
• Phenobarbital
• Rifampin
• St. John's wort

Contraindications

Velpanat Tablets are contraindicated in patients who are allergic to sofosbuvir or velpatasvir or any of the other ingredients in Velpanat Tablets.

Special Populations

Velpanat Tablets are safe and effective in patients with compensated cirrhosis. However, Velpanat Tablets are not recommended for patients with decompensated cirrhosis. Velpanat Tablets are also safe and effective in patients with kidney disease. However, dose adjustments may be necessary in patients with severe kidney disease.

Pregnancy and Lactation

There is limited information on the safety and efficacy of Velpanat Tablets in pregnant or lactating women. Therefore, Velpanat Tablets should only be used in pregnant or lactating women if the potential benefits outweigh the potential risks.

Conclusion

Velpanat Tablets are a highly effective and safe treatment for chronic hepatitis C virus infection. They are a short-course treatment, typically lasting only 8 or 12 weeks. Velpanat Tablets are also effective against all six major genotypes of HCV and in patients with compensated cirrhosis.

If you are diagnosed with chronic hepatitis C virus infection, Velpanat Tablets should be considered as a first-line treatment option. Talk to your doctor today to learn more about Velpanat Tablets and how they can help you achieve a sustained virologic response (SVR), which is the functional cure of HCV infection.