Natdac

Availability:
Natdac 60 Trade Information Minimum Order Quantity 1.00 Unit of Measure Piece/Pieces Payment Terms Paypal, Others Supply Ability As Per Requirement Per Week Delivery Time 7-15 Days Packaging Details Carton Boxes Packaging. Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Africa Main Domestic Market All India Certifications Certified [...]

Product Description

Natdac 60 Trade Information
Minimum Order Quantity 1.00 Unit of Measure Piece/Pieces
Payment Terms Paypal, Others Supply Ability As Per Requirement Per Week
Delivery Time 7-15 Days Packaging Details Carton Boxes Packaging.
Main Export Market(s) Asia, Australia, Central America, North America, South America, Eastern Europe, Western Europe, Africa Main Domestic Market All India
Certifications Certified Products.
Natdac 60 Export Countries Details: Countries: Russsia, Ukrain, Korea, Ajbakistan, Kajistan, Poland, USA, India, Philipines & China
Product Description

Buy Natdac 60 Mg & Natdac Daclatasvir Tablets Online from Suppliers, Exporters & Distributors of India

We are identified as one of the leading organizations, engaged in offering Natdac Tablets. Our expert agents procure these tablets from the certified vendors of the market. The tablets are indicated in combination with sofosbuvir for the treatment of patient with chronic hepatitis C virus. Natdac Daclatasvir Tablets are recommended to be taken orally with or without meals. We offer these tablets at pocket friendly prices.

Features:

  • Effective antiviral drugs
  • Taken orally
  • Longer shelf life

Daclatasvir

Natdac Product Description

Natdac 60 is an inhibitor of non-structural protein 5A (NS5A).

Each film-coated tablet contains Daclatasvir equivalent to Daclatasvir 30 mg or 60 mg.

INDICATIONS AND USAGE

Natdac 60 is indicated in combination with Sofosbuvir for the treatment of patient with chronic hepatitis C virus (HCV) genotype 3 infection.

DOSAGE AND ADMINISTRATION

Treatment with Natdac 60 should be initiated and monitored by physician experienced in the management of chronic hepatitis C. The recommended dose of Natdac 60 is 60 mg once daily to be taken orally with or without meals. MyDacla 60  must be administered in combination with other medical products.The Packeges inserts of the medicinal products in the regimen should also be consulated before initiation of therapy with Natdac 60. Recommended reginmens and treatment duration are provided below.

Recommended regimens and treatment duration for Natdac 60 combination therapy

 

 HCV genotype and patient  population  Treatment  Duration
 Genotype 3 without cirrhosis  Daclatasvir + sofosbuvir  12 weeks
 Genotype 3 with cirrhosis  Daclatasvir + sofosbuvir  24 weeks

 

Dose modification, interruption and discontinuation

Dose modification of Natdac 60 to manage adverse reactions is not recommended.There is no virologic treatment stopping rules that apply to the combination of Natdac 60 with sofosbuvir.

CONTRAINDICATIONS

Hypersensitivity to the active substance or to any of the excipients Coadministration with medicinal products that strongly induce cytochrome P450 3A4 (CYP3A4) and P-glycoprotein transporter (P-gp) and thus may lead to lower exposure and loss of efficacy of Daclatasvir. These active substances include but are not limited to phenytoin, carbamazepine, oxcarbazepine, rifampicin, rifapentine, systemic dexamethasone, and the herbal product St John’s wort (Hypericum perforatum).

WARNINGS AND PRECAUTIONS

Natdac 60 must not be administered as monotherapy.DeciHeptm must be administered in combination with other medicinal products for the the treatment of chronic HCV infection.

General

The safety and efficacy of the combination of Daclatasvir and sofosbuvir have been evaluated in a limited number of patients with cirrhosis in clinical studies.

Decompensates liver disease

The safety and efficacy of MyDacla 60 in the treatment of HCV infection in patients with decompensated liver disease have not been established.

Retreatment with MyDacla 60

The efficacy of MyDacla 60 as part of a retreatment regimen in patients with prior exposure to a NS5A inhibitor has not been established.

Pregnancy and contraception requirements

Natdac 60 should not be used during pregnancy or in women of childbearing potential not using contraception.Use of highly effective contraception should be continued for 5 weeks after completion of Daclatasvir therapy.

ADVERSE REACTIONS

Adverse reactions in clinical trials.

The most common adverse reactions(>=10%) were fatigue and headache, aneamia,hot flush,nausea in subjects treated with 8, 12, or 24 weeks of Ledipasvir + Sofosbuvir.

DRUG INTERACTIONS

Contraindications of concomitant use

Natdac 60  is contraindication in combination with medicinal products that strongly induce CYP3A4 and P-gp,e.g. phenytoin,carbamazepine,oxcarbazepine,rifampicin,rifabutin,rifapen-tine,systemic dexamethasone, and the herbal product St John’s wort (Hypericum perforatum), and thus may lead to lower exposure and loss of efficacy of Daclatasvir.

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